# Asian Oral Microbiome Synthetic Dataset — Executive One-Pager (v2026.06)

**AI Bio-Data Factory Lab** · Production-Verified · jerry820402@hotmail.com

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## What Is It?

The **world's first Chinese-anchored oral microbiome multi-omics synthetic dataset** — 3,872 production records, each linking **genomic sequence + taxonomic abundance + clinical disease triplet** (periodontal / cardiovascular / diabetes).

Built on **8× NVIDIA A800 DDP** with **Evo** foundation model inference, anchored to **121 global WGS backbones** and **Chinese oral clinical seeds**.

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## Why It Matters (3 Pain Points → 3 Solutions)

| Pain Point | Our Solution |
|------------|--------------|
| **Western Bias** — >80% global omics data is Caucasian-centric | **100% Chinese population signal** — unlock Asian market AI |
| **Compliance Hell** — real patient DNA takes years + $M to legalize | **100% Synthetic** — zero natural persons, GDPR / cross-border exempt |
| **Compute Sink** — 8× A800 + Evo engineering = months of sunk cost | **Instant deploy** — we absorbed compute; you get ready-to-train JSON-L |

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## Audit Bulletin (OVERALL PASSED)

| Dimension | Method | Result | Gate |
|-----------|--------|--------|------|
| Community Structure | PERMANOVA | **p = 0.994** | ✓ PASS |
| Manifold Distance | MMD | **0.060** | ✓ PASS |
| Clinical Triplet | PERMANOVA | **p = 0.415** | ✓ PASS |
| Alpha Diversity | Shannon | **p = 0.599** | ✓ PASS |
| Abundance Profile | Spearman | **r = 1.000** | ✓ PASS |

*Synthetic n=3,872 vs Chinese reference n=30 · Cyclic Dirichlet calibration (concentration=500)*

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## What's in the Preview (Free on Hugging Face)

- **38 stratified JSON-L records** (`preview_dataset.jsonl`)
- **`validate_preview.py`** — run PERMANOVA/MMD locally in 30 seconds
- **Full whitepaper** — technical & commercial deep-dive

**Preview:** https://huggingface.co/datasets/jerry982/BioFactory-Asian-Oral-Microbiome-Preview

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## Full Commercial Access

| Channel | Offering |
|---------|----------|
| **Snowflake Marketplace** | Quarterly drops / enterprise buyout |
| **Direct License** | 3,872-record encrypted zip + Validation_Report.json + MD5 |

**Contact:** jerry820402@hotmail.com

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## 中文摘要

全球首个**华人锚定**口腔多组学**全合成**数据集：3872 条三联记录（基因序列 + 菌群丰度 + 临床标签），经 Cyclic Dirichlet 流形校准，**PERMANOVA p=0.994、MMD=0.060、临床三元组 p=0.415**，终局审计 **OVERALL PASSED**。100% 合成数据，零自然人映射，天然规避 GDPR 与跨境临床数据合规壁垒。预览版 38 条已开源，完整商业授权请联系 **jerry820402@hotmail.com**。

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*Copyright © 2026 AI Bio-Data Factory Lab*