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ADNI Mini v1.3 selection
Cohort
- 1,200 subjects and one baseline T1w scan per subject
- 450 CN, 500 MCI, 250 AD
- 600 Female, 600 Male
- 286 CN amyloid-positive participants, all retained within the 450-CN quota
v1.3 changes from v1.2
- Retired LDELTOTAL slope and amygdala slope.
- Added RAVLT 30-minute delayed recall and RAVLT learning (sum of AVTOT1-5) annualized 48-month slopes.
- Added FreeSurfer 7 bilateral entorhinal cortical-thickness annualized 48-month slope, calculated as mean(ST24TA, ST83TA) and excluding explicit temporal-lobe QC failures.
- Retained CN A+ to MCI/AD within 36 months, with a strict CN plus amyloid-positive gate.
- Added CN A+ restricted variants of ADAS13, both RAVLT, hippocampus, ventricles, and entorhinal thickness slopes.
Final coverage
| Task | N | Events |
|---|---|---|
| MCI to AD within 3y | 450 | 169 |
| CN A+ to MCI/AD within 3y | 187 | 39 |
| ADAS13 slope, 48m | 973 | - |
| RAVLT delayed slope, 48m | 975 | - |
| RAVLT learning slope, 48m | 977 | - |
| Hippocampus slope, 48m | 925 | - |
| Ventricle slope, 48m | 925 | - |
| Entorhinal thickness slope, 48m | 878 | - |
| CN A+ ADAS13 slope, 48m | 187 | - |
| CN A+ RAVLT delayed slope, 48m | 189 | - |
| CN A+ RAVLT learning slope, 48m | 189 | - |
| CN A+ hippocampus slope, 48m | 164 | - |
| CN A+ ventricle slope, 48m | 164 | - |
| CN A+ entorhinal thickness slope, 48m | 143 | - |
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