Unnamed: 0
int64
0
10k
title
stringlengths
3
547
abstract
stringlengths
10
122k
200
Treatment of idiopathic spasmodic torticollis with botulinum‐A toxin: a pilot study of 19 patients
Nineteen patients with spasmodic torticollis, unresponsive to standard therapy, were administered local injections of botulinum‐A toxin into the affected muscles. During an average follow‐up period of 11.5 months, a more than 25% improvement was noted in 14 of 19 patients. All those with purely focal dystonia and 9 of ...
201
A high frequency of allopolyploid speciation in the gymnospermous genus Ephedra and its possible association with some biological and ecological features
The origin and evolution of polyploids have been studied extensively in angiosperms and ferns but very rarely in gymnosperms. With the exception of three species of conifers, all natural polyploid species of gymnosperms belong to Ephedra, in which more than half of the species show polyploid cytotypes. Here, we investi...
202
Distribution of split DnaE inteins in cyanobacteria
Inteins are genetic elements found inside the coding regions of different host proteins and are translated in frame with them. The intein‐encoded protein region is removed by an autocatalytic protein‐splicing reaction that ligates the host protein flanks with a peptide bond. This reaction can also occur in trans with t...
203
Could preventive intranasal interferon lower the morbidity in children prone to respiratory illness?
Recent studies have demonstrated that rhinovirus infections can be prevented in the family setting through use of intranasal interferon sprays which are commenced when another family member develops a cold. One hundred and twenty‐seven children aged 4–9 years who had been hospitalized during their first year of life fo...
204
Use of Protein A in the Serum‐in‐Agar Diffusion Method in Immune Electron Microscopy for Detection of Virus Particles in Cell Culture
A modified technique using protein A in the serum‐in‐agar (SIA) method for immune electron microscopy (IEM) was presented. Grids coated with staphylococcal protein A were floated on samples mounted on agar containing 2% antiserum and incubated at 37 C, for 60 min. After washing and staining, the grids were observed in ...
205
The integral membrane protein from a virulent isolate of transmissible gastroenteritis virus: molecular characterization, sequence and expression in Escherichia coli
Subgenomic mRNA from a virulent isolate of porcine transmissible gastroenteritis virus (TGEV) was used to produce cDNA clones. Part of a new clone and a previously reported clone were sequenced and used to construct the viral gene for integral membrane protein. A single open reading frame (ORF) encoding a polypeptide o...
206
Looking Forward to Serving SID
null
207
Differential Expression of the Major Histocompatibility Antigen Complex (MHC) on a Series of Burkitt's Lymphoma Lines
We compared the expressions of class I and class II major histocompatibility antigen complex (MHC) on the surface of Jijoye and P3HR‐1 cells of Burkitt's lymphoma sublines. Jijoye cells had a large amount of class I and class II MHC antigens, whereas these antigens were less expressed on P3HR‐1 cells. On a subline of P...
208
Australia was indeed the “lucky country” in the recent worldwide SARS epidemic
null
209
Sequence of the nucleoprotein gene from a virulent British field isolate of transmissible gastroenteritis virus and its expression in Saccharomyces cerevisiae
Subgenomic mRNA from a virulent isolate of porcine transmissible gastroenteritis virus (TGEV) was used to produce cDNA which was sequenced. Two non‐overlapping open reading frames (ORFs) were identified. The largest, encoding a polypeptide of 382 amino acids (relative molecular mass (M(r)) 43 483), was shown to be the ...
210
Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2003–2004
This review is the third update of the original review, published in 1999, on the application of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings the topic to the end of 2004. Both fundamental studies and applications are covered. The ...
211
The dual role of thymidine phosphorylase in cancer development and chemotherapy
Thymidine phosphorylase (TP), also known as “platelet‐derived endothelial cell growth factor” (PD‐ECGF), is an enzyme, which is upregulated in a wide variety of solid tumors including breast and colorectal cancers. TP promotes tumor growth and metastasis by preventing apoptosis and inducing angiogenesis. Elevated level...
212
Hydrocephalus in Suckling Rats Infected Intracerebrally with Mouse Hepatitis Virus, MHV‐A59
After intracerebral inoculation of mouse hepatitis virus, MHV‐A59 strain, into 3‐ to 5‐day‐old Wistar rats, some survivors at 14 days postinoculation (p.i.) were found to lack the cerebral cortex and to have an accumulation of a considerable amount of cerebrospinal fluid. The virus titer in the brain increased exponent...
213
Ancestral acquisitions, gene flow and multiple evolutionary trajectories of the type three secretion system and effectors in Xanthomonas plant pathogens
Deciphering the evolutionary history and transmission patterns of virulence determinants is necessary to understand the emergence of novel pathogens. The main virulence determinant of most pathogenic proteobacteria is the type three secretion system (T3SS). The Xanthomonas genus includes bacteria responsible for numero...
214
Preventing local transmission of SARS: lessons from Singapore
null
215
SARS and its effect on medical education in Hong Kong
null
216
The receptor for Bacillus thuringiensis CrylA(c) delta‐endotoxin in the brush border membrane of the lepidopteran Manduca sexta is aminopeptidase N
A 120 kDa glycoprotein in the larval midgut membrane of the Iepidopteran Manduca sexta, previously identified as a putative receptor for Bacillus thuringiensis CrylA(c) δ‐endotoxin, has been purified by a combination of protoxin affinity Chromatography and anion exchange chromatography. In immunoblotting experiments, t...
217
Molecular characteristics and pathogenic assessment of porcine epidemic diarrhoea virus isolates from the 2018 endemic outbreaks on Jeju Island, South Korea
Since the 2013–2014 incursion of the virulent G2b porcine epidemic diarrhoea virus (PEDV) pandemic strains in South Korea, frequent moderate‐scale regional outbreaks have recurred. In particular, areas of Jeju Island with extensive swine production have faced repeated epidemics since the re‐emergence in 2014. The curre...
218
Emergence and adaptive evolution of Nipah virus
Since its first emergence in 1998 in Malaysia, Nipah virus (NiV) has become a great threat to domestic animals and humans. Sporadic outbreaks associated with human‐to‐human transmission caused hundreds of human fatalities. Here, we collected all available NiV sequences and combined phylogenetics, molecular selection, s...
219
Whether the GFR measured by renal scintigraphy under non-steady state conditions for critically ill patients with AKI can be used as a predictive parameter for clinical events
null
220
Impact of intestinal parasites on microbiota and cobalamin gene sequences: a pilot study
BACKGROUND: Approximately 30% of children worldwide are infected with gastrointestinal parasites. Depending on the species, parasites can disrupt intestinal bacterial microbiota affecting essential vitamin biosynthesis. METHODS: Stool samples were collected from 37 asymptomatic children from a previous cross-sectional ...
221
Initially elevated arterial lactate as an independent predictor of poor outcomes in severe acute pancreatitis
BACKGROUND: The present study aimed to investigate the relationships between arterial lactate levels and outcomes in severe acute pancreatitis. METHODS: The study retrospectively analyzed the medical data of 329 patients with severe acute pancreatitis from January 2014 to February 2019. We compared baseline characteris...
222
Non‐human viruses developed as therapeutic agent for use in humans
Viruses usually infect a restricted set of host species, and only in rare cases does productive infection occur outside the natural host range. Infection of a new host species can manifest as a distinct disease. In this respect, the use of non‐human viruses in clinical therapy may be a cause for concern. It could provi...
223
From the Editors
null
224
The ubiquitin‐proteasome system in positive‐strand RNA virus infection
Positive‐stranded RNA viruses, like many other viruses, have evolved to exploit the host cellular machinery to their own advantage. In eukaryotic cells, the ubiquitin‐proteasome system (UPS) that serves as the major intracellular pathway for protein degradation and modification plays a crucial role in the regulation of...
225
Abstracts for the Annual Scientific Meeting of the Thoracic Society of Australia & New Zealand ‘Maintaining Lung Health from Cradle to Grave’ 7–12 April 2000, Melbourne, Australia
null
226
Reasoned Decision Making Without Math? Adaptability and Robustness in Response to Surprise
Many real‐world planning and decision problems are far too uncertain, too variable, and too complicated to support realistic mathematical models. Nonetheless, we explain the usefulness, in these situations, of qualitative insights from mathematical decision theory. We demonstrate the integration of info‐gap robustness ...
227
Clinical relevance of necrotizing change in patients with community‐acquired pneumonia
BACKGROUND AND OBJECTIVE: Few studies have analysed a large number of patients with necrotizing pneumonia (NP) diagnosed based on computed tomography (CT) scans. The aim of the present study was to document the incidence and clinical features of NP in patients with community‐acquired pneumonia (CAP). METHODS: This retr...
228
EDITORIAL
null
229
POSTER PRESENTATION
null
230
AETIOLOGY OF COMMUNITY ACQUIRED PNEUMONIA WITH FEVER AND THE PRESENTATION AND PROGNOSIS OF VIRAL INFECTION: A PROSPECTIVE OBSERVATIONAL STUDY
null
231
Viruses and autoimmunity: an affair but not a marriage contract
Viruses are considered as causative agents and contributors to lesion expression in autoimmune disease, notions best supported by studies in animal model systems. This review discusses relationships between virus infection and autoimmunity focusing on mechanisms by which they could induce autoreactivity. The popular id...
232
Loop mediated isothermal amplification (LAMP): a new generation of innovative gene amplification technique; perspectives in clinical diagnosis of infectious diseases
Loop mediated isothermal amplification (LAMP) is a powerful innovative gene amplification technique emerging as a simple rapid diagnostic tool for early detection and identification of microbial diseases. The whole procedure is very simple and rapid wherein the amplification can be completed in less than 1 h under isot...
233
Saffold virus, an emerging human cardiovirus
Saffold virus (SAFV) is an emerging human cardiovirus that has been shown to be ubiquitous. Initial studies of SAFV focused on respiratory and gastrointestinal infection; however, it has also recently been associated with diverse clinical symptoms including the endocrine, cardiovascular, and neurological systems. Given...
234
Restoration Practices Have Positive Effects on Breeding Bird Species of Concern in the Chihuahuan Desert
Woody plant encroachment into grasslands is a global concern. Efforts to restore grasslands often assume that removal of woody plants benefits biodiversity but assumptions are rarely tested. In the Chihuahuan Desert of the Southwestern United States, we tested whether abundances of grassland specialist bird species wou...
235
Abstracts for the 9th Congress of the Asian Pacific Society of Respirology 10‐13 December, Hong Kong
null
236
COPD SIG: Poster Session 2
null
237
Borna disease virus
Borna disease virus (BDV) is unique amongst animal RNA viruses in its molecular biology and capacity to cause persistent, noncytolytic CNS‐infection in a wide variety of host species. Unlike other non‐segmented negative‐strand RNA animal viruses, BDV replicates in the nucleus of the host cell where splicing is employed...
238
Characterizing degradation products of peptides containing N‐terminal Cys residues by (off‐line high‐performance liquid chromatography)/matrix‐assisted laser desorption/ionization quadrupole time‐of‐flight measurements
A transformation analogous to the well‐known conversion of an N‐terminal glutamine residue to pyroglutamic acid is the cyclization of an N‐terminal carboxamidomethylated cysteine residue (the normal product of alkylation with iodoacetamide). This yields 5‐oxothiomorpholine‐3‐carboxylic acid, with the same 17 Da mass lo...
239
Paediatric SIG: Poster Session
null
240
1‐E3: COPD 4
null
241
TSANZ Oral Presentations
null
242
Invited Speakers
null
243
The Effect of Mask Use on the Spread of Influenza During a Pandemic
Face masks have traditionally been used in general infection control, but their efficacy at the population level in preventing transmission of influenza viruses has not been studied in detail. Data from published clinical studies indicate that the infectivity of influenza A virus is probably very high, so that transmis...
244
Effects of Surface Material, Ventilation, and Human Behavior on Indirect Contact Transmission Risk of Respiratory Infection
Infectious particles can be deposited on surfaces. Susceptible persons who contacted these contaminated surfaces may transfer the pathogens to their mucous membranes via hands, leading to a risk of respiratory infection. The exposure and infection risk contributed by this transmission route depend on indoor surface mat...
245
Pathogen inactivation/reduction of platelet concentrates: turning theory into practice
Background Pathogen reduction technology (PRT) has been proven to reduce the residual risk of transmission of infectious agents. Reduction of various contaminating bacteriae, viruses and parasites by few to several log steps and efficiency to prevent GVHD has been shown. Aim To evaluate and compare advantages and disad...
246
Serum Lipase Activity in Young Dogs With Acute Enteritis or Gastroenteritis
Blood serum lipase activity was determined in 48 young dogs with acute enteritis or gastroenteritis due to canine parvovirus (16 cases) and presumably to other infectious agents (32 cases). Elevated serum lipase activity (> 500 U/L) was found in 13 dogs (27.1%) with values ranging from 800 to 2,780 U/L. The hyperlipase...
247
Print‐only Abstracts
null
248
Threats to blood safety posed by emerging protozoan pathogens
null
249
ULTRASONOGRAPHIC AND PATHOLOGIC FEATURES OF INTESTINAL SMOOTH MUSCLE HYPERTROPHY IN FOUR CATS
The ultrasonographic findings for four cats with intestinal smooth muscle hypertrophy are described. In two cats, intestinal smooth muscle hypertrophy was associated with chronic enteritis. In the remaining two cats, intestinal smooth muscle hypertrophy affected the intestinal tract proximal to stenosis due to alimenta...
250
Globalization and blood safety
Globalization may be viewed as the growing interdependence of countries worldwide through the increasing volume and variety of cross‐border transactions in goods and services, and also through the more rapid and widespread diffusion of technology. Globalization is not just an economic phenomenon, although it is frequen...
251
CONTRAST‐ENHANCED ULTRASONOGRAPHY OF THE SMALL BOWEL IN HEALTHY CATS
We characterized the pattern of ultrasonographic contrast enhancement of the small intestinal wall using a commercial contrast medium (Sonovue(®)) in 10 healthy awake cats. Subjectively, a rapid intense enhancement of the serosal and submucosal layers was followed by gradual enhancement of the entire wall section durin...
252
Oral Abstracts
null
253
Oral abstracts
null
254
ABSTRACTS FROM THE 2014 EUROPEAN VETERINARY DIAGNOSTIC IMAGING ANNUAL CONFERENCE: Utrecht, The Netherlands, August 27 – August 30, 2014
null
255
MAGNETIC RESONANCE IMAGING OF THE NORMAL AND DISEASED FELINE MIDDLE EAR
The magnetic resonance imaging appearance of the feline middle ear is described in three healthy cats and in five cats with middle ear disease. Owing to the good spatial resolution, multiplanar slice orientation as well as display high contrast resolution of soft tissue, in particular fluids, MR imaging was helpful pri...
256
Abstract of 29th Regional Congress of the ISBT
null
257
This won't hurt …: Tiny needles deliver drugs painlessly
null
258
Environment: Toxic cleanups get a boost
null
259
Biomedicine: Acid blockers stop stomach ulcers, too
null
260
Unbuttoning normalcy – on cosmopolitical events
The history of social research can be read as a critical endeavour inasmuch as it unbuttons the normalcy of collective action by multiplying relevant actors and the imaginaries of social reality. I show how paying close sociological attention to what I call cosmopolitical events, offers one approach to such a conceptio...
261
Out of China: SARS virus' genome hints at independent evolution
null
262
Biomedicine: SARS vaccine triggers immunity in monkeys
null
263
Electronic thread: Fiber transistor may lead to woven circuits
null
264
Environment: When testosterone gets down and dirty
null
265
Vaccines: Kids' vaccine guards adults too, for now
null
266
Evaluating the ALERT algorithm for local outbreak onset detection in seasonal infectious disease surveillance data
Estimation of epidemic onset timing is an important component of controlling the spread of seasonal infectious diseases within community healthcare sites. The Above Local Elevated Respiratory Illness Threshold (ALERT) algorithm uses a threshold‐based approach to suggest incidence levels that historically have indicated...
267
A revision of the western Palaearctic species of Urophora Robineau‐Desvoidy (Diptera: Tephritidae)
Abstract A key is provided to twenty‐four western Palaearctic species of Urophora Robineau‐Desvoidy. The hosts of twenty‐three species which attack Asteraceae are listed, including those being used or investigated as possible weed biocontrol agents. The species are divided into four species groups and the differing hos...
268
Identification and discrimination of Electrogena species by numerical methods (Ephemeroptera: Heptageniidae)
Abstract. Nine species of Electrogena from thirty‐one populations were investigated on the basis of five meristic and five ratio characters of the larvae. The attribution of populations to species was checked by a cluster analysis based on the generalized distances between pairs. Groups representing species were then s...
269
Biomedicine: SARs virus can spread in lab animals
null
270
Phylogeny and classification of the Signiphoridae (Hymenoptera: Chalcidoidea)
Abstract. A data set consisting of twenty‐eight anatomical characters scored for twenty‐eight terminal taxa representing the world fauna of Signiphoridae was analysed using parsimony and compatibility methods. The Coccophaginae (Aphelinidae) and the Azotinae (Aphelinidae) were used as outgroups to establish polarity of...
271
Astronomy: X‐ray images highlight galaxy collisions
null
272
Biomedicine: Human antibody halts SARS in hamsters
null
273
Books for late summer: From genius genes to tyrannosaur musings
null
274
Fine toothcomb: New fossils add to primate‐origins debate
null
275
Emerging pathogens: Drug‐resistant staph causes more pneumonia
null
276
The next MTBE: Contamination from fuel additives could spread
null
277
A Nanostructured Microfluidic Immunoassay Platform for Highly Sensitive Infectious Pathogen Detection
Rapid and simultaneous detection of multiple potential pathogens by portable devices can facilitate early diagnosis of infectious diseases, and allow for rapid and effective implementation of disease prevention and treatment measures. The development of a ZnO nanorod integrated microdevice as a multiplex immunofluoresc...
278
Bacterial ecology: New bacteria linked to vaginal infections
null
279
Significance of new lung infiltrates in outpatients after lung and heart–lung transplantation
BACKGROUND: Infection and rejection represent major complications following lung transplantation and are often associated with pulmonary infiltrates. The differential diagnosis of these infiltrates depends on their timing after transplantation. The aim of this study was to characterize lung transplant recipients (LTR) ...
280
Scientific Section
null
281
Hepatitis E Virus and Related Viruses in Animals
Hepatitis E is an acute human liver disease in healthy individuals which may eventually become chronic. It is caused by the hepatitis E virus (HEV) and can have a zoonotic origin. Nearly 57,000 people die yearly from hepatitis E‐related conditions. The disease is endemic in both developing and developed countries with ...
282
Abstract Presentations from the AABB Annual Meeting San Diego, CA ctober 7‐10, 2017
null
283
Ribosomal frameshifting in yeast viruses
Proper maintenance of translational reading frame by ribosomes is essential for cell growth and viability. In the last 10 years it has been shown that a number of viruses induce ribosomes to shift reading frame in order to regulate the expression of gene products having enzymatic functions. Studies on ribosomal framesh...
284
Relationships between Floodplain Lake Fish Communities and Environmental Variables in a Large River‐Floodplain Ecosystem
Floodplain lakes of large river systems contain fish habitats that are not found elsewhere within the river, and these lakes have a diversity of environmental conditions that vary in space and time. Our objective was to examine relationships between floodplain lake fish communities and environmental variables associate...
285
Viral attacks on the blood supply: the impact of severe acute respiratory syndrome in Beijing
null
286
Infectivity of Cryptosporidium parvum oocysts is retained upon intestinal passage through a migratory water‐fowl species (Canada goose, Branta canadensis)
Summary Five Cryptosporidium‐free Canada geese (Branta canadensis) were individually orally dosed with 3–5 × 10(6) Cryptosporidium parvum oocysts infectious to neonatal BALB/c mice. After intestinal passage, inoculum‐derived oocysts extracted from goose faeces established severe infection in 14 neonatal BALB/c mice (in...
287
Abstracts of the Joint Conference of the Canadian Society for Transfusion Medicine, Canadian Blood Services and Héma‐Québec, Banff, Alberta, Canada, 21–24 April 2005
null
288
Classification of Texas Reservoirs in Relation to Limnology and Fish Community Associations
I used cluster analysis to examine associations among 20 fish species to develop a classification scheme for 132 large Texas reservoirs. Five major groups of reservoirs were identified by cluster analysis based on species associations. Of 29 reservoirs surveyed previously, 76% were classified into the same species asso...
289
Current awareness on yeast
In order to keep subscribers up‐to‐date with the latest developments in their field, this current awareness service is provided by John Wiley & Sons and contains newly‐published material on yeasts. Each bibliography is divided into 10 sections. 1 Books, Reviews & Symposia; 2 General; 3 Biochemistry; 4 Biotechnology; 5 ...
290
Molecular delimitation of clades within New World species of the "spiny solanums" (Solanum subg. Leptostemonum)
Solanum subg. Leptostemonum contains approximately 350–450 species, including the cultivated eggplant, S. melongena. Most species placed in this subgenus form a monophyletic group, the Leptostemonum clade, characterized by the presence of stellate hairs and prickles, leading to the common name of "spiny solanums". Here...
291
Tempering the risk: Rift Valley fever and bioterrorism
null
292
Seasonal Diversity, Abundance, and Distribution of Ichthyoplankton in Tamiahua Lagoon, Western Gulf of Mexico
The ichthyoplanktonic community of Tamiahua Lagoon, Veracruz, Mexico, was studied throughout an annual cycle. Major concentrations of larvae occurred in the central portion of the lagoon, occasionally along the channels, but never at the inlets. The cycle of larva abundance was correlated with cycles of salinity and te...
293
Infections after T‐replete haploidentical transplantation and high‐dose cyclophosphamide as graft‐versus‐host disease prophylaxis
BACKGROUND: Recently, a platform of T‐cell replete haploidentical hematopoietic stem cell transplantation (haplo‐HSCT) using post‐transplant cyclophosphamide (Cy) has shown high reproducibility and acceptable safety profile. METHOD: This prospective cohort analysis allowed us to collect data on infections among 70 cons...
294
Design, Synthesis, and Evaluation of Bioactive Small Molecules
Collaborative research projects between chemists, biologists, and medical scientists have inevitably produced many useful drugs, biosensors, and medical instrumentation. Organic chemistry lies at the heart of drug discovery and development. The current range of organic synthetic methodologies allows for the constructio...
295
Oral Presentation Sessions
null
296
Risks associated with red blood cell transfusions: potential benefits from application of pathogen inactivation
BACKGROUND: Red blood cell (RBC) transfusion risks could be reduced if a robust technology for pathogen inactivation of RBC (PI‐RBCs) were to be approved. MATERIALS AND METHODS: Estimates of per‐unit and per‐patient aggregate infectious risks for conventional RBCs were calculated; the latter used patient diagnosis as a...
297
Abstract Presentations from the AABB Annual Meeting Boston, MA, October 13–16, 2018
null
298
An approach to the control of disease transmission in pig‐to‐human xenotransplantation
Abstract: Although several major immunologic hurdles need to be overcome, the pig is currently considered the most likely source animal of cells, tissues and organs for transplantation into humans. Concerns have been raised with regard to the potential for the transfer of infectious agents with the transplanted organ t...
299
Nosocomial Infection in the Intensive Care Unit
null